1st leukemia patient dosed with SMART101 at MSK
January 23, 2023
A groundbreaking technology
Pioneering thymus-empowered
T-cell therapy platform to fight cancer and infection
Smart Immune is a clinical-stage biotechnology company developing ProTcell, a thymus-empowered T-cell therapy platform to fully and rapidly re-arm the immune system, enabling next generation allogeneic T-cell therapies for all.
The ProTcell platform
Through its patented ex vivo lymphoid technology, Smart Immune has developed a T-cell progenitor-based cell therapy platform, called the ProTcell platform. It has been designed to enable rapid and full re-arming of the immune system, so patients can fight life-threatening disorders. Our lymphoid progenitors have a remarkable dual potential of differentiation:
- T lineage: when directly infused to patients, they complete their differentiation into the thymus recipient to become polyclonal and fully efficient T cells.
- NK lineage: when further cultured ex vivo through a dedicated process they can differentiate into early NK effectors.
For the first time in human medicine, Smart Immune is enabling access to thymus-empowered, sustainable, allogeneic T-cell progenitors, minimising donor matching requirements and accelerating full immune recovery.
