July 6, 2022

Marcel R. M. van den Brink, MD, PhD Appointed Chairman of Smart Immune’s Scientific Advisory Board

Smart Immune SAS, a clinical-stage biotechnology company developing ProTcell™, a thymus-empoweredcell therapy platform to fully and rapidly re-arm the immune system, enabling next generation allogeneic T-cell therapies, announced today that Dr. Marcel van den Brink has been appointed Chairmanof its Scientific Advisory Board (SAB).  

Dr. van den Brink is internationally renowned for his work in the field of bone marrow transplantation, the gut microbiome, and immunotherapy at New York’s Memorial Sloan Kettering Cancer Center, where he is Head of the Division of Hematologic Malignancies. He has received prestigious prizes and honors including the 2022 E.Donnall Thomas Award from the American Society for Transplantation and Cellular Therapy (ASTCT).

Dr. van den Brink has been collaborating with Smart Immune since 2020. The ongoing research program addresses some of the challenges of thymic involution and potential CAR ProTcellTMapplications.

“We are so excited to have Dr. van den Brink join our SAB as Chairman, and see it as a validation of the Company’s scientific robustness,” commented Karine Rossignol, Chief Executive Officer and Co-founder of Smart Immune. “His world-class expertise in bone marrow transplantation, thymic regeneration, development and research into blood cancer targeted therapies will be invaluable as we advance our ProTcellTMplatform development with the goal of improving the prognosis of immune-compromised patients.”

“I am thrilled to become Chairman of the Scientific Advisory Board at Smart Immune,” said Dr. Marcel van den Brink.Smart Immune is developing precursor T-cells to help improve the immune repertoire.This could benefit people who require allogeneic bone marrow transplants but also the platform has the potential to generate long-lasting, targeted immune-oncology therapies.”

Please see attached the full press release.